Tissue Specificity | Highly expressed in placenta, liver and fetal skin. Weakly expressed in fetal epiphyseal cartilage, fetal liver, fibroblast, lung and skeletal muscle. Expressed also in fibrous cap of carotid atherosclerotic lesions. |
Post Translational Modifications | N-glycosylation plays no role in the catalytic activity. |
Function | Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. |
Protein Name | Prolyl 4-Hydroxylase Subunit Alpha-34-Ph Alpha-3Procollagen-Proline -2-Oxoglutarate-4-Dioxygenase Subunit Alpha-3 |
Database Links | Reactome: R-HSA-1650814 |
Cellular Localisation | Endoplasmic Reticulum Lumen |
Alternative ELISA Names | Prolyl 4-Hydroxylase Subunit Alpha-3 ELISA kit4-Ph Alpha-3 ELISA kitProcollagen-Proline -2-Oxoglutarate-4-Dioxygenase Subunit Alpha-3 ELISA kitP4HA3 ELISA kitUNQ711 ELISA kitPRO1374 ELISA kit |
output | |
Information sourced from Uniprot.org