Tissue Specificity | Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain. |
Post Translational Modifications | |
Function | Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. |
Protein Name | P2y Purinoceptor 12P2y12Adp-Glucose ReceptorAdpg-RP2t(AcP2y(AcP2y(CycP2y12 Platelet Adp ReceptorP2y(AdpSp1999 |
Database Links | Reactome: R-HSA-392170Reactome: R-HSA-417957Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | P2y Purinoceptor 12 ELISA kitP2y12 ELISA kitAdp-Glucose Receptor ELISA kitAdpg-R ELISA kitP2t(Ac ELISA kitP2y(Ac ELISA kitP2y(Cyc ELISA kitP2y12 Platelet Adp Receptor ELISA kitP2y(Adp ELISA kitSp1999 ELISA kitP2RY12 ELISA kitHORK3 ELISA kit |
output | |
Information sourced from Uniprot.org