| Short Description : | Recombinant-Active-Human OSMR/IL-31RB-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to bind rhOSM in the presence of rhgp130 in a functional ELISA. |
| Gene Symbol: | OSMR |
| Gene ID: | 9180 |
| Uniprot ID: | OSMR_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Glu28-Ser739 |
| Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
| Protein Name | Oncostatin-M-Specific Receptor Subunit BetaInterleukin-31 Receptor Subunit BetaIl-31 Receptor Subunit BetaIl-31r Subunit BetaIl-31r-BetaIl-31rb |
| Database Links | Reactome: R-HSA-6788467 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Oncostatin-M-Specific Receptor Subunit Beta proteinInterleukin-31 Receptor Subunit Beta proteinIl-31 Receptor Subunit Beta proteinIl-31r Subunit Beta proteinIl-31r-Beta proteinIl-31rb proteinOSMR proteinOSMRB protein |
Information sourced from Uniprot.org
