Human OLFM4 protein (Recombinant) (N-GST & C-His) (STJP006822)

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STJP006822
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human OLFM4-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: OLFM4
Gene ID: 10562
Uniprot ID: OLFM4_HUMAN
Immunogen Region: Lys206-Gln510
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.
Function May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.
Protein Name Olfactomedin-4
Olm4
Antiapoptotic Protein Gw112
G-Csf-Stimulated Clone 1 Protein
Hgc-1
Holfd
Database Links Reactome: R-HSA-6798695
Cellular Localisation Secreted
Extracellular Space
Mitochondrion
Subcellular Location Is Not Clearly Defined: Has Been Shown To Be Secreted
But Also In The Mitochondrion
Cytoplasm And Plasma Membrane And In The Nucleus
Alternative Protein Names Olfactomedin-4 protein
Olm4 protein
Antiapoptotic Protein Gw112 protein
G-Csf-Stimulated Clone 1 Protein protein
Hgc-1 protein
Holfd protein
OLFM4 protein
GW112 protein
UNQ362 protein
PRO698 protein

Information sourced from Uniprot.org