| Post Translational Modifications | Tyrosine phosphorylated. Phosphorylated by TSSK4 on Ser-95. |
| Function | Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly. |
| Protein Name | Outer Dense Fiber Protein 2CenexinOuter Dense Fiber Of Sperm Tails Protein 2 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCell ProjectionCiliumCentrioleSpindle PoleFlagellumLocalized At The Microtubule Organizing Centers In Interphase And Spindle Poles In MitosisLocalized At The Distal/Subdistal Appendages Of Mother Centrioles |
| Alternative Protein Names | Outer Dense Fiber Protein 2 proteinCenexin proteinOuter Dense Fiber Of Sperm Tails Protein 2 proteinODF2 protein |
Information sourced from Uniprot.org
