Name: Human OCIL/CLEC2D protein (Recombinant) (His-Tag) (STJP018045)
SKU: STJP018045
Availability: InStock

Human OCIL/CLEC2D protein (Recombinant) (His-Tag) (STJP018045)

SKU:

STJP018045

£134.50 - £738.50

Short Description :	Recombinant-Human OCIL/CLEC2D-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:	SDS-PAGE/Denatured
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration:	1 mg/mL
Formulation:	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Storage Instruction:	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CLEC2D
Gene ID:	29121
Uniprot ID:	CLC2D_HUMAN
Accession Number:	NP_037401
Immunogen:	Human
Immunogen Region:	60-191aa
Immunogen Sequence:	MGSSHHHHHH SSGLVPRGSH MGSRANCHQE PSVCLQAACP ESWIGFQRKC FYFSDDTKNW TSSQRFCDSQ DADLAQVESF QELNFLLRYK GPSDHWIGLS REQGQPWKWI NGTEWTRQFP ILGAGECAYL NDKGASSARH YTERKWICSK SDIHV

Tissue Specificity	Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells.
Post Translational Modifications	N-glycosylated.
Function	Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.
Protein Name	C-Type Lectin Domain Family 2 Member D Lectin-Like Nk Cell Receptor Lectin-Like Transcript 1 Llt-1 Osteoclast Inhibitory Lectin
Database Links	Reactome: R-HSA-198933
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein Isoform 2: Endoplasmic Reticulum Isoform 4: Endoplasmic Reticulum
Alternative Protein Names	C-Type Lectin Domain Family 2 Member D protein Lectin-Like Nk Cell Receptor protein Lectin-Like Transcript 1 protein Llt-1 protein Osteoclast Inhibitory Lectin protein CLEC2D protein CLAX protein LLT1 protein OCIL protein

Information sourced from Uniprot.org

Model	Name	Host	Clonality	Reactivity	Application
STJP007307	Human CLEC2D/OCIL/LLT1 protein (Recombinant) (N-His) (STJP007307)	E.coli			ELISA/Immunogen/SDS-PAGE/WB
STJP014042	Mouse CLEC2D/OCIL/LLT1 protein (Recombinant) (N-His) (STJP014042)	Mammalian Cells			ELISA/WB
STJP008618	Human CLEC2D/OCIL/LLT1 protein (Recombinant) (C-Fc) (STJP008618)	Mammalian Cells			ELISA/Immunogen/SDS-PAGE/WB
STJA0027054	Anti-CLEC2D/OCIL/LLT1 antibody [SAA0110] (STJA0027054)	Mouse	Monoclonal	Human	FC
STJA0028808	Anti-CLEC2D/OCIL/LLT1 antibody [SAA0110] {FITC} (STJA0028808)	Mouse	Monoclonal	Human	FC

Human OCIL/CLEC2D protein (Recombinant) (His-Tag) (STJP018045)

General Information