Human NUMB protein (Recombinant) (N-His) (STJP004827)

SKU:
STJP004827
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NUMB-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NUMB
Gene ID: 8650
Uniprot ID: NUMB_HUMAN
Immunogen Region: Leu376-Phe482
Immunogen: Homo sapiens (Human)
Function Regulates clathrin-mediated receptor endocytosis. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
Protein Name Protein Numb Homolog
H-Numb
Protein S171
Database Links Reactome: R-HSA-2122948
Reactome: R-HSA-437239
Reactome: R-HSA-5610780
Reactome: R-HSA-5632684
Reactome: R-HSA-9725554
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Endosome Membrane
Localizes To Perinuclear Endosomes In An Aak1-Dependent Manner
Alternative Protein Names Protein Numb Homolog protein
H-Numb protein
Protein S171 protein
NUMB protein
C14orf41 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E. coli
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E. coli
STJP007878 Human GPAT3 protein (Recombinant) (N-His) (STJP007878) E. coli
STJP007867 Human NAP1L4 protein (Recombinant) (N-His) (STJP007867) E. coli
STJP007854 Human EGLN1 protein (Recombinant) (N-His) (STJP007854) E. coli

Related Products

!