Human NUCB2 protein (Recombinant) (N-His) (STJP005091)

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STJP005091
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Short Description :Recombinant-Human NUCB2-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:NUCB2
Gene ID:4925
Uniprot ID:NUCB2_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Val25-Asp104
Function Calcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance. In intestinal epithelial cells, plays a role in the inhibition of hepatic glucose production via MC4R receptor leading to increased cyclic adenosine monophosphate (cAMP) levels and glucagon-like peptide 1 (GLP-1) secretion.
Protein Name Nucleobindin-2
Dna-Binding Protein Nefa
Epididymis Secretory Protein Li 109
Gastric Cancer Antigen Zg4
Prepronesfatin Cleaved Into - Nesfatin-1
Database Links
Cellular Localisation Golgi Apparatus
Membrane
Peripheral Membrane Protein
Cytoplasm
Secreted
Endoplasmic Reticulum
Nucleus Envelope
Golgi Retention Is Mediated By Its N-Terminal Region
Nesfatin-1: Secreted
Alternative Protein Names Nucleobindin-2 protein
Dna-Binding Protein Nefa protein
Epididymis Secretory Protein Li 109 protein
Gastric Cancer Antigen Zg4 protein
Prepronesfatin Cleaved Into - Nesfatin-1 protein
NUCB2 protein
NEFA protein

Information sourced from Uniprot.org