| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human NT5M-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | NT5M |
| Gene ID: | 56953 |
| Uniprot ID: | NT5M_HUMAN |
| Immunogen Region: | Val38-Cys228 |
| Immunogen: | Homo sapiens (Human) |
| Function | Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. |
| Protein Name | 5'(3'-Deoxyribonucleotidase - Mitochondrial5' -3'-Nucleotidase - MitochondrialDeoxy-5'-Nucleotidase 2Dnt-2 |
| Database Links | Reactome: R-HSA-73621 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | 5'(3'-Deoxyribonucleotidase - Mitochondrial protein5' -3'-Nucleotidase - Mitochondrial proteinDeoxy-5'-Nucleotidase 2 proteinDnt-2 proteinNT5M proteinDNT2 protein |
Information sourced from Uniprot.org