Human NREP protein (Recombinant) (His-Tag) (STJP018544)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human NREP-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NREP |
| Gene ID | 9315 |
| Uniprot ID | NREP_HUMAN |
| Accession Number | NP_004763 |
| Immunogen | Human |
| Immunogen Region | 1-68aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMVYYPEL FVWVSQEPFP NKDMEGRLPK GRLPVPKEVN RKKNDETNAA SLTPLGSSEL RSPRISYLHF F |
Additional Info
| Tissue Specificity | Expressed in lung (at protein level). |
| Post Translational Modifications | Phosphorylated on Ser-59. Phosphorylation decreases stability and activity. |
| Function | May have roles in neural function. Ectopic expression augments motility of gliomas. Also promotes axonal regeneration. May also have functions in cellular differentiation. Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis. Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3. May play a role in the regulation of alveolar generation. |
| Protein Name | Neuronal Regeneration-Related ProteinNeuronal Protein 3.1Protein P311 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Neuronal Regeneration-Related Protein proteinNeuronal Protein 3.1 proteinProtein P311 proteinNREP proteinC5orf13 proteinP311 protein |
Information sourced from Uniprot.org