Human NR2E1 protein (Recombinant) (N-His) (STJP015034)

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STJP015034
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Short Description :Recombinant-Human NR2E1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-81°C for twelve months from the date of receipt.
Endotoxin:Please contact us for further information.
Gene Symbol:NR2E1
Gene ID:7101
Uniprot ID:NR2E1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met175-Ile385
Function Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity. May be involved in retinoic acid receptor (RAR) regulation in retinal cells.
Protein Name Nuclear Receptor Subfamily 2 Group E Member 1
Nuclear Receptor Tlx
Protein Tailless Homolog
Tll
Htll
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-8943724
Cellular Localisation Nucleus
Alternative Protein Names Nuclear Receptor Subfamily 2 Group E Member 1 protein
Nuclear Receptor Tlx protein
Protein Tailless Homolog protein
Tll protein
Htll protein
NR2E1 protein
TLX protein

Information sourced from Uniprot.org

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