Human NPTN (Neuroplastin) Sandwich ELISA Kit (STJE0011046)
SPECIFICATIONS
General Information
| Short Description | This NPTN Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.052ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | NPTN |
| Gene ID | 27020 |
| Uniprot ID | NPTN_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level). |
| Post Translational Modifications | |
| Function | Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. Also acts as a chaperone for ATP2B1.stabilizes ATP2B1 and increases its ATPase activity. Promotes localization of XKR8 at the cell membrane. |
| Protein Name | NeuroplastinStromal Cell-Derived Receptor 1Sdr-1 |
| Database Links | Reactome: R-HSA-977443 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Postsynaptic Density |
| Alternative ELISA Names | Neuroplastin ELISA kitStromal Cell-Derived Receptor 1 ELISA kitSdr-1 ELISA kitNPTN ELISA kitSDFR1 ELISA kitSDR1 ELISA kit |
| output |
Information sourced from Uniprot.org