Tissue Specificity | Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level). |
Post Translational Modifications | |
Function | Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. Also acts as a chaperone for ATP2B1.stabilizes ATP2B1 and increases its ATPase activity. Promotes localization of XKR8 at the cell membrane. |
Protein Name | NeuroplastinStromal Cell-Derived Receptor 1Sdr-1 |
Database Links | Reactome: R-HSA-977443 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Postsynaptic Density |
Alternative ELISA Names | Neuroplastin ELISA kitStromal Cell-Derived Receptor 1 ELISA kitSdr-1 ELISA kitNPTN ELISA kitSDFR1 ELISA kitSDR1 ELISA kit |
output | |
Information sourced from Uniprot.org