Human NPR1/NPR-A protein (Recombinant) (C-Fc) (STJP010178)

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STJP010178
€351.88 - €2,526.88
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Host: Mammalian Cells
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NPR1/NPR-A-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NPR1
Gene ID: 4881
Uniprot ID: ANPRA_HUMAN
Immunogen Region: Met1-Glu473
Immunogen: Homo sapiens (Human)
Function Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Plays an essential role in the regulation of endothelial cell senescence and vascular aging. Upon activation by ANP or BNP, stimulates the production of cyclic guanosine monophosphate (cGMP) that promotes vascular tone and volume homeostasis by activation of protein kinase cGMP-dependent 1/PRKG1 and subsequently PRKAA1, thereby controlling blood pressure and maintaining cardiovascular homeostasis.
Protein Name Atrial Natriuretic Peptide Receptor 1
Atrial Natriuretic Peptide Receptor Type A
Anp-A
Anpr-A
Npr-A
Guanylate Cyclase A
Gc-A
Database Links Reactome: R-HSA-5578768
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Atrial Natriuretic Peptide Receptor 1 protein
Atrial Natriuretic Peptide Receptor Type A protein
Anp-A protein
Anpr-A protein
Npr-A protein
Guanylate Cyclase A protein
Gc-A protein
NPR1 protein
ANPRA protein

Information sourced from Uniprot.org