Human NPR1 (Natriuretic Peptide Receptor 1) Sandwich ELISA Kit (STJE0011036)

Human NPR1 (Natriuretic Peptide Receptor 1) Sandwich ELISA Kit (STJE0011036)

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STJE0011036
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.117ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This NPR1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: NPR1
Gene ID: 4881
Uniprot ID: ANPRA_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylation of the protein kinase-like domain is required for full activation by ANP.
Function Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Plays an essential role in the regulation of endothelial cell senescence and vascular aging. Upon activation by ANP or BNP, stimulates the production of cyclic guanosine monophosphate (cGMP) that promotes vascular tone and volume homeostasis by activation of protein kinase cGMP-dependent 1/PRKG1 and subsequently PRKAA1, thereby controlling blood pressure and maintaining cardiovascular homeostasis.
Protein Name Atrial Natriuretic Peptide Receptor 1
Atrial Natriuretic Peptide Receptor Type A
Anp-A
Anpr-A
Npr-A
Guanylate Cyclase A
Gc-A
Database Links Reactome: R-HSA-5578768
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative ELISA Names Atrial Natriuretic Peptide Receptor 1 ELISA kit
Atrial Natriuretic Peptide Receptor Type A ELISA kit
Anp-A ELISA kit
Anpr-A ELISA kit
Npr-A ELISA kit
Guanylate Cyclase A ELISA kit
Gc-A ELISA kit
NPR1 ELISA kit
ANPRA ELISA kit
output

Information sourced from Uniprot.org

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