Function | Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. |
Protein Name | Puromycin-Sensitive AminopeptidasePsaCytosol Alanyl AminopeptidaseAap-S |
Database Links | Reactome: R-HSA-983168 |
Cellular Localisation | CytoplasmCytosolNucleus |
Alternative Protein Names | Puromycin-Sensitive Aminopeptidase proteinPsa proteinCytosol Alanyl Aminopeptidase proteinAap-S proteinNPEPPS proteinPSA protein |
Information sourced from Uniprot.org