Human NOS1AP protein (Recombinant) (N-His) (STJP003334)

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STJP003334
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NOS1AP-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NOS1AP
Gene ID: 9722
Uniprot ID: CAPON_HUMAN
Immunogen Region: Thr285-Val506
Immunogen: Homo sapiens (Human)
Function Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4. In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation.
Protein Name Carboxyl-Terminal Pdz Ligand Of Neuronal Nitric Oxide Synthase Protein
C-Terminal Pdz Ligand Of Neuronal Nitric Oxide Synthase Protein
Nitric Oxide Synthase 1 Adaptor Protein
Cellular Localisation Cell Projection
Filopodium
Podosome
Alternative Protein Names Carboxyl-Terminal Pdz Ligand Of Neuronal Nitric Oxide Synthase Protein protein
C-Terminal Pdz Ligand Of Neuronal Nitric Oxide Synthase Protein protein
Nitric Oxide Synthase 1 Adaptor Protein protein
NOS1AP protein
CAPON protein
KIAA0464 protein

Information sourced from Uniprot.org