Human Noggin/NOG protein (Recombinant) (C-His) (STJP001239)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenActive Recombinant Human Noggin/NOG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln28-Cys232) of human Noggin (Accession #NP_005441.1) fused with a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human Noggin/NOG-C-His protein was developed in hek293 cells using the region Gln28-Cys232. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | 1.Measured by its binding ability in a functional ELISA. Immobilized Human BMP2 at 1 Mu g/mL (100 Mu L/well) can bind Noggin with a linear range of 2-57 ng/mL.|2. Measured by its binding ability in a functional ELISA.Immobilized Human BMP4 at 0.5 Mu |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | NOG |
| Gene ID | 9241 |
| Uniprot ID | NOGG_HUMAN |
| Immunogen | Active Recombinant Human Noggin/NOG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln28-Cys232) of human Noggin (Accession #NP_005441.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Region | Gln28-Cys232 |
| Immunogen Sequence | QHYLHIRPAPSDNLPLVDLI EHPDPIFDPKEKDLNETLLR SLLGGHYDPGFMATSPPEDR PGGGGGAAGGAEDLAELDQL LRQRPSGAMPSEIKGLEFSE GLAQGKKQRLSKKLRRKLQM WLWSQTFCPVLYAWNDLGSR FWPRYVKVGSCFSKRSCSVP EGMVCKPSKSVHLTVLRWRC QRRGGQRCGWIPIQYPIISE CKCSC |
Additional Info
| Protein Name | Noggin |
| Database Links | Reactome: R-HSA-201451Reactome: R-HSA-9793380 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Noggin proteinNOG protein |
Information sourced from Uniprot.org