Human NKX6-1 protein (Recombinant) (N-GST) (STJP005074)

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STJP005074
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NKX6-1-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NKX6-1
Gene ID: 4825
Uniprot ID: NKX61_HUMAN
Immunogen Region: Met1-Ser367
Immunogen: Homo sapiens (Human)
Function Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals.
Protein Name Homeobox Protein Nkx-6.1
Homeobox Protein Nk-6 Homolog A
Database Links Reactome: R-HSA-210745
Reactome: R-HSA-210747
Cellular Localisation Nucleus
Alternative Protein Names Homeobox Protein Nkx-6.1 protein
Homeobox Protein Nk-6 Homolog A protein
NKX6-1 protein
NKX6A protein

Information sourced from Uniprot.org

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