| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human NKp44-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Gene Symbol: | NCR2 |
| Gene ID: | 9436 |
| Uniprot ID: | NCTR2_HUMAN |
| Immunogen Region: | GLN22-PRO190 |
| Immunogen: | Optimized DNA sequence encoding Human Natural Killer Cell Receptor NKp44 (GLN22-PRO190) extracellular domain including a C-terminal His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells. |
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 2Lymphocyte Antigen 95 HomologNk Cell-Activating ReceptorNatural Killer Cell P44-Related ProteinNk-P44Nkp44Cd Antigen Cd336 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-2172127 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Natural Cytotoxicity Triggering Receptor 2 proteinLymphocyte Antigen 95 Homolog proteinNk Cell-Activating Receptor proteinNatural Killer Cell P44-Related Protein proteinNk-P44 proteinNkp44 proteinCd Antigen Cd336 proteinNCR2 proteinLY95 protein |
Information sourced from Uniprot.org