| Short Description : | Recombinant-Human NIPSNAP2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | NIPSNAP2 |
| Gene ID: | 2631 |
| Uniprot ID: | NIPS2_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ala60-Gln286 |
| Function | Protein involved in mitophagy by facilitating recruitment of the autophagy machinery required for clearance of damaged mitochondria. Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy, such as autophagy receptors (CALCOCO2/NDP52, NBR1, SQSTM1/p62, TAX1BP1 and WDFY3/ALFY) and ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2). |
| Protein Name | Protein Nipsnap Homolog 2Nipsnap2Glioblastoma-Amplified Sequence |
| Database Links | Reactome: R-HSA-9013407Reactome: R-HSA-9013409 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Protein Names | Protein Nipsnap Homolog 2 proteinNipsnap2 proteinGlioblastoma-Amplified Sequence proteinNIPSNAP2 proteinGBAS protein |
Information sourced from Uniprot.org