| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human NID2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | NID2 |
| Gene ID: | 22795 |
| Uniprot ID: | NID2_HUMAN |
| Immunogen Region: | Gly1107-Gly1373 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Highly N-glycosylated. Highly O-glycosylated. Contains chondroitin sulfate which is attached at Ser-452 and at either Ser-358 or Ser-359. |
| Function | Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions. |
| Protein Name | Nidogen-2Nid-2Osteonidogen |
| Database Links | Reactome: R-HSA-3000157 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement Membrane |
| Alternative Protein Names | Nidogen-2 proteinNid-2 proteinOsteonidogen proteinNID2 protein |
Information sourced from Uniprot.org
