| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | NRP2 |
| Gene ID: | 8828 |
| Uniprot ID: | NRP2_HUMAN |
| Immunogen: | Recombinant Human Neuropilin-2/NRP2/VEGF165R2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Tyr855) of human Neuropilin 2/NRP2 (Accession #NP_003863.2) fused with a 6×His tag at the C-termi |
| Immunogen Sequence: | MDMFPLTWVFLALYFSRHQV RGQPDPPCGGRLNSKDAGYI TSPGYPQDYPSHQNCEWIVY APEPNQKIVLNFNPHFEIEK HDCKYDFIEIRDGDSESADL LGKHCGNIAPPTIISSGSML YIKFTSDYARQGAGFSLRYE IFKTGSEDCSKNFTSPNGTI ESPGFPEKYPHNLDCTFTIL AKPKMEIILQFLIFDLEHDP LQVGEGDCKYDWLDIWDGIP HVGPLIGKYCGTKTPSELR |
| Function | High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. (Microbial infection) Acts as a receptor for human cytomegalovirus pentamer-dependent entry in epithelial and endothelial cells. |
| Protein Name | Neuropilin-2Vascular Endothelial Cell Growth Factor 165 Receptor 2 |
| Database Links | Reactome: R-HSA-194306Reactome: R-HSA-447038 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform S9: Secreted |
| Alternative Protein Names | Neuropilin-2 proteinVascular Endothelial Cell Growth Factor 165 Receptor 2 proteinNRP2 proteinVEGF165R2 protein |
Information sourced from Uniprot.org