Human Neuropilin-2/NRP2/VEGF165R2 protein (Recombinant) (C-hFc) (STJP002986)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Neuropilin-2/NRP2/VEGF165R2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Tyr855 ) of Human Neuropilin-2/NRP2/VEGF165R2 (Accession #NP_003863.2) fused with hFc tag at the
General Information
| Short Description | Recombinant-Human Neuropilin-2/NRP2/VEGF165R2-C-hFc protein was developed in hek293 cells using the region Met1-Tyr855 . For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | NRP2 |
| Gene ID | 8828 |
| Uniprot ID | NRP2_HUMAN |
| Immunogen | Recombinant Human Neuropilin-2/NRP2/VEGF165R2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Tyr855 ) of Human Neuropilin-2/NRP2/VEGF165R2 (Accession #NP_003863.2) fused with hFc tag at the |
| Immunogen Region | Met1-Tyr855 |
| Immunogen Sequence | KGDLVKPSRGQLVNCTCENP HCKRPICQGAWCTVVLVREQ GRHPQVYRGCGSLNQELCLG RPTEFVNHHCCYRSFCNHNV SLMLEATQTPSEEPEVDA |
Additional Info
| Function | High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. (Microbial infection) Acts as a receptor for human cytomegalovirus pentamer-dependent entry in epithelial and endothelial cells. |
| Protein Name | Neuropilin-2Vascular Endothelial Cell Growth Factor 165 Receptor 2 |
| Database Links | Reactome: R-HSA-194306Reactome: R-HSA-447038 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform S9: Secreted |
| Alternative Protein Names | Neuropilin-2 proteinVascular Endothelial Cell Growth Factor 165 Receptor 2 proteinNRP2 proteinVEGF165R2 protein |
Information sourced from Uniprot.org