| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.125ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description : | This NET1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | NET1 |
| Gene ID: | 10276 |
| Uniprot ID: | ARHG8_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | |
| Function | Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. |
| Protein Name | Neuroepithelial Cell-Transforming Gene 1 ProteinProto-Oncogene P65 Net1Rho Guanine Nucleotide Exchange Factor 8 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-8980692Reactome: R-HSA-9013026 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative ELISA Names | Neuroepithelial Cell-Transforming Gene 1 Protein ELISA kitProto-Oncogene P65 Net1 ELISA kitRho Guanine Nucleotide Exchange Factor 8 ELISA kitNET1 ELISA kitARHGEF8 ELISA kit |
| output |
Information sourced from Uniprot.org
