Human NDRG2 (N-myc Downstream Regulated Gene 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017287)

Human NDRG2 (N-myc Downstream Regulated Gene 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017287)

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STJE0017287
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.115ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This NDRG2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: NDRG2
Gene ID: 57447
Uniprot ID: NDRG2_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues.absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).
Post Translational Modifications
Function Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.
Protein Name Protein Ndrg2
N-Myc Downstream-Regulated Gene 2 Protein
Protein Syld709613
Database Links
Cellular Localisation Cytoplasm
Perinuclear Region
Cell Projection
Growth Cone
In Neurons
Seems To Concentrate At Axonal Growth Cone
Perinuclear In Neurons
Alternative ELISA Names Protein Ndrg2 ELISA kit
N-Myc Downstream-Regulated Gene 2 Protein ELISA kit
Protein Syld709613 ELISA kit
NDRG2 ELISA kit
KIAA1248 ELISA kit
SYLD ELISA kit
output

Information sourced from Uniprot.org

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