| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.117ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description : | This NCF1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | NCF1 |
| Gene ID: | 653361 |
| Uniprot ID: | NCF1_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Detected in peripheral blood monocytes and neutrophils (at protein level). |
| Post Translational Modifications | Phosphorylated by PRKCD.phosphorylation induces activation of NCF1 and NADPH oxidase activity. |
| Function | NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). |
| Protein Name | Neutrophil Cytosol Factor 1Ncf-147 Kda Autosomal Chronic Granulomatous Disease Protein47 Kda Neutrophil Oxidase FactorNcf-47kNeutrophil Nadph Oxidase Factor 1Nox Organizer 2Nox-Organizing Protein 2Sh3 And Px Domain-Containing Protein 1aP47-Phox |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-1236973Reactome: R-HSA-3299685Reactome: R-HSA-4420097Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013423 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative ELISA Names | Neutrophil Cytosol Factor 1 ELISA kitNcf-1 ELISA kit47 Kda Autosomal Chronic Granulomatous Disease Protein ELISA kit47 Kda Neutrophil Oxidase Factor ELISA kitNcf-47k ELISA kitNeutrophil Nadph Oxidase Factor 1 ELISA kitNox Organizer 2 ELISA kitNox-Organizing Protein 2 ELISA kitSh3 And Px Domain-Containing Protein 1a ELISA kitP47-Phox ELISA kitNCF1 ELISA kitNOXO2 ELISA kitSH3PXD1A ELISA kit |
| output |
Information sourced from Uniprot.org
