| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.119ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description : | This NBC4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | SLC4A5 |
| Gene ID: | 57835 |
| Uniprot ID: | S4A5_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | Highest expression observed in liver, spleen and testis.moderate expression in the choroid plexus, hippocampus, cerebrum and cerebellum of brain, and in kidney cortex and kidney medulla. Also observed in heart, pancreas, muscle, lung, placenta, stomach and small intestine. Weakest expression seen in peripheral blood lymphocytes, colon, duodenum, jejunum, ileum and skeletal muscle. Isoform 3: Expressed in the brain, heart, kidney, testis, pancreas, muscle and peripheral blood leukocytes. |
| Post Translational Modifications | |
| Function | Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. |
| Protein Name | Electrogenic Sodium Bicarbonate Cotransporter 4 Nbce2 Solute Carrier Family 4 Member 5 |
| Database Links | Reactome: R-HSA-425381 |
| Cellular Localisation | Apical Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane Expressed In The Apical Plasma Membrane Domain Of A Subset Of Collecting Ducts In The Renal Medulla |
| Alternative ELISA Names | Electrogenic Sodium Bicarbonate Cotransporter 4 ELISA kit Nbce2 ELISA kit Solute Carrier Family 4 Member 5 ELISA kit SLC4A5 ELISA kit NBC4 ELISA kit |
| output |
Information sourced from Uniprot.org