Human NANS protein (Recombinant) (His-Tag) (STJP016924)

Name: Human NANS protein (Recombinant) (His-Tag) (STJP016924)
SKU: STJP016924
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP016924

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Short Description	Recombinant-Human NANS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 1mM DTT, 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	NANS
Gene ID	54187
Uniprot ID	SIAS_HUMAN
Accession Number	NP_061819
Immunogen	Human
Immunogen Region	1-359aa
Immunogen Sequence	MGSSHHHHHH SSGLVPRGSH MPLELELCPG RWVGGQHPCF IIAEIGQNHQ GDLDVAKRMI RMAKECGADC AKFQKSELEF KFNRKALERP YTSKHSWGKT YGEHKRHLEF SHDQYRELQR YAEEVGIFFT ASGMDEMAVE FLHELNVPFF KVGSGDTNNF PYLEKTAKKG RPMVISSGMQ SMDTMKQVYQ IVKPLNPNFC FLQCTSAYPL QPEDVNLRVI SEYQKLFP

Tissue Specificity	Ubiquitous.
Function	Catalyzes the condensation of phosphoenolpyruvate (PEP) and N-acetylmannosamine 6-phosphate (ManNAc-6-P) to synthesize N-acetylneuraminate-9-phosphate (Neu5Ac-9-P). Also catalyzes the condensation of PEP and D-mannose 6-phosphate (Man-6-P) to produce 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate (KDN-9-P). Neu5Ac-9-P and KDN-9-P are the phosphorylated forms of sialic acids N-acetylneuraminic acid (Neu5Ac) and deaminoneuraminic acid (KDN), respectively. Required for brain and skeletal development.
Protein Name	N-Acetylneuraminate-9-Phosphate Synthase 3-Deoxy-D-Glycero-D-Galacto-Nononate 9-Phosphate Synthase N-Acetylneuraminic Acid Phosphate Synthase Nans Sialic Acid Phosphate Synthase Sialic Acid Synthase
Database Links	Reactome: R-HSA-4085001
Cellular Localisation
Alternative Protein Names	N-Acetylneuraminate-9-Phosphate Synthase protein 3-Deoxy-D-Glycero-D-Galacto-Nononate 9-Phosphate Synthase protein N-Acetylneuraminic Acid Phosphate Synthase protein Nans protein Sialic Acid Phosphate Synthase protein Sialic Acid Synthase protein NANS protein SAS protein

Information sourced from Uniprot.org