| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human Naglazyme/Galsulfase, N-Fc-N-Fc protein was developed from mammalian cells and has a target region of N-Fc. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | ARSB |
| Gene ID: | 411 |
| Uniprot ID: | ARSB_HUMAN |
| Immunogen Region: | Ala38-Met533 |
| Immunogen: | Homo sapiens (Human) |
| Function | Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation. Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium. In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels. |
| Protein Name | Arylsulfatase BAsbN-Acetylgalactosamine-4-SulfataseG4s |
| Database Links | Reactome: R-HSA-1663150Reactome: R-HSA-2024101Reactome: R-HSA-2206285Reactome: R-HSA-6798695Reactome: R-HSA-9840310 |
| Cellular Localisation | LysosomeCell Surface |
| Alternative Protein Names | Arylsulfatase B proteinAsb proteinN-Acetylgalactosamine-4-Sulfatase proteinG4s proteinARSB protein |
Information sourced from Uniprot.org