Human MYOD1 protein (Recombinant) (N-His) (STJP004127)

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STJP004127
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MYOD1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MYOD1
Gene ID: 4654
Uniprot ID: MYOD1_HUMAN
Immunogen Region: Met1-Leu320
Immunogen: Homo sapiens (Human)
Function Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.
Protein Name Myoblast Determination Protein 1
Class C Basic Helix-Loop-Helix Protein 1
Bhlhc1
Myogenic Factor 3
Myf-3
Database Links Reactome: R-HSA-525793
Reactome: R-HSA-9839394
Cellular Localisation Nucleus
Alternative Protein Names Myoblast Determination Protein 1 protein
Class C Basic Helix-Loop-Helix Protein 1 protein
Bhlhc1 protein
Myogenic Factor 3 protein
Myf-3 protein
MYOD1 protein
BHLHC1 protein
MYF3 protein
MYOD protein

Information sourced from Uniprot.org