Human MYH10 protein (Recombinant) (N-His) (STJP004624)

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STJP004624
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MYH10-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MYH10
Gene ID: 4628
Uniprot ID: MYH10_HUMAN
Immunogen Region: His438-Pro716
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated by ABL2.
Function Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension.this function is mechanically antagonized by MYH9. (Microbial infection) Acts as a receptor for herpes simplex virus 1/HHV-1 envelope glycoprotein B.
Protein Name Myosin-10
Cellular Myosin Heavy Chain - Type B
Myosin Heavy Chain 10
Myosin Heavy Chain - Non-Muscle Iib
Non-Muscle Myosin Heavy Chain B
Nmmhc-B
Non-Muscle Myosin Heavy Chain Iib
Nmmhc Ii-B
Nmmhc-Iib
Database Links Reactome: R-HSA-3928663
Reactome: R-HSA-416572
Reactome: R-HSA-5625740
Reactome: R-HSA-5625900
Reactome: R-HSA-5627117
Reactome: R-HSA-5627123
Cellular Localisation Cell Projection
Lamellipodium
Colocalizes With Mcc At The Leading Edge Of Migrating Cells
Cell Membrane
(Microbial Infection) Localizes At The Surface Of The Cell Membrane Following Infection By Herpes Simplex Virus 1/Hhv-1
Alternative Protein Names Myosin-10 protein
Cellular Myosin Heavy Chain - Type B protein
Myosin Heavy Chain 10 protein
Myosin Heavy Chain - Non-Muscle Iib protein
Non-Muscle Myosin Heavy Chain B protein
Nmmhc-B protein
Non-Muscle Myosin Heavy Chain Iib protein
Nmmhc Ii-B protein
Nmmhc-Iib protein
MYH10 protein

Information sourced from Uniprot.org