Tissue Specificity | Detected in placenta (at protein level). Detected in cerebrospinal fluid and fibroblasts (at protein level). Highly expressed in kidney, also detected on liver and spleen. Expressed by proximal tubular cells of the kidney (at protein level). Expression highly increases during chronic kidney disease and autosomal dominant polycystic kidney disease, where is detected in cysts. |
Post Translational Modifications | |
Function | In kidney, has anti-inflammatory and anti-fibrotic properties by limiting the induction of chemokines, fibronectin and collagen expression in response to TGB1 and pro-inflammatory stimuli. |
Protein Name | Matrix-Remodeling-Associated Protein 5Adhesion Protein With Leucine-Rich Repeats And Immunoglobulin Domains Related To PerlecanAdlican |
Database Links | |
Cellular Localisation | Secreted |
Alternative ELISA Names | Matrix-Remodeling-Associated Protein 5 ELISA kitAdhesion Protein With Leucine-Rich Repeats And Immunoglobulin Domains Related To Perlecan ELISA kitAdlican ELISA kitMXRA5 ELISA kit |
output | |
Information sourced from Uniprot.org