| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human MXD1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | MXD1 |
| Gene ID: | 4084 |
| Uniprot ID: | MAD1_HUMAN |
| Immunogen Region: | Met1-Ser145 |
| Immunogen: | Homo sapiens (Human) |
| Function | Component of a transcriptional repressor complex together with MAX. In complex with MAX binds to the core DNA sequence 5'-CACGATG-3'. Antagonizes MYC transcriptional activity by competing with MYC for MAX binding. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding. |
| Protein Name | Max Dimerization Protein 1Max Dimerizer 1Protein Mad |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Max Dimerization Protein 1 proteinMax Dimerizer 1 proteinProtein Mad proteinMXD1 proteinMAD protein |
Information sourced from Uniprot.org