Human MX2 protein (Recombinant) (His-Tag) (STJP018614)

Name: Human MX2 protein (Recombinant) (His-Tag) (STJP018614)
SKU: STJP018614
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018614

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Short Description	Recombinant-Human MX2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE/Denatured
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	MX2
Gene ID	4600
Uniprot ID	MX2_HUMAN
Accession Number	NP_002454.1
Immunogen	Human
Immunogen Region	626-715aa
Immunogen Sequence	MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSIGIH LNAYFLETSK RLANQIPFII QYFMLRENGD SLQKAMMQIL QEKNRYSWLL QEQSETATKR RILKERIYRL TQARHALCQF SSKEIH

Function	Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression.
Protein Name	Interferon-Induced Gtp-Binding Protein Mx2 Interferon-Regulated Resistance Gtp-Binding Protein Mxb Myxovirus Resistance Protein 2 P78-Related Protein
Database Links	Reactome: R-HSA-1169408 Reactome: R-HSA-909733
Cellular Localisation	Cytoplasm Nucleus Nuclear Pore Complex Localization To Nuclear Pores Requires Gtp-Binding
Alternative Protein Names	Interferon-Induced Gtp-Binding Protein Mx2 protein Interferon-Regulated Resistance Gtp-Binding Protein Mxb protein Myxovirus Resistance Protein 2 protein P78-Related Protein protein MX2 protein

Information sourced from Uniprot.org