Human MTUS1 protein (Recombinant) (N-His) (STJP006194)

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STJP006194
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Short Description :Recombinant-Human MTUS1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:MTUS1
Gene ID:57509
Uniprot ID:MTUS1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met1031-Arg1270
Function Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
Protein Name Microtubule-Associated Tumor Suppressor 1
At2 Receptor-Binding Protein
Angiotensin-Ii Type 2 Receptor-Interacting Protein
Mitochondrial Tumor Suppressor 1
Database Links
Cellular Localisation Mitochondrion
Golgi Apparatus
Cell Membrane
Nucleus
In Neurons
Translocates Into The Nucleus After Treatment With Angiotensin-Ii
Isoform 1: Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cytoplasm
Spindle
Localizes With The Mitotic Spindle During Mitosis And With The Intercellular Bridge During Cytokinesis
Alternative Protein Names Microtubule-Associated Tumor Suppressor 1 protein
At2 Receptor-Binding Protein protein
Angiotensin-Ii Type 2 Receptor-Interacting Protein protein
Mitochondrial Tumor Suppressor 1 protein
MTUS1 protein
ATBP protein
ATIP protein
GK1 protein
KIAA1288 protein
MTSG1 protein

Information sourced from Uniprot.org