Human MTAP protein (Recombinant) (N-His) (STJP007478)

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STJP007478
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MTAP-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MTAP
Gene ID: 4507
Uniprot ID: MTAP_HUMAN
Immunogen Region: Met1-His283
Immunogen: Homo sapiens (Human)
Function Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
Protein Name S-Methyl-5'-Thioadenosine Phosphorylase
5'-Methylthioadenosine Phosphorylase
Mta Phosphorylase
Mtap
Mtapase
Database Links Reactome: R-HSA-1237112
Reactome: R-HSA-8950505
Cellular Localisation Cytoplasm
Nucleus
Alternative Protein Names S-Methyl-5'-Thioadenosine Phosphorylase protein
5'-Methylthioadenosine Phosphorylase protein
Mta Phosphorylase protein
Mtap protein
Mtapase protein
MTAP protein
MSAP protein

Information sourced from Uniprot.org