Function | Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. |
Protein Name | Methionine-R-Sulfoxide Reductase B2 - MitochondrialMsrb2 |
Database Links | Reactome: R-HSA-5676934 |
Cellular Localisation | Mitochondrion |
Alternative Protein Names | Methionine-R-Sulfoxide Reductase B2 - Mitochondrial proteinMsrb2 proteinMSRB2 proteinCBS-1 proteinMSRB proteinCGI-131 protein |
Information sourced from Uniprot.org