Human MRPL58 protein (Recombinant) (N-His) (STJP008355)

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STJP008355
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MRPL58-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MRPL58
Gene ID: 3396
Uniprot ID: ICT1_HUMAN
Immunogen Region: Asp71-Asp206
Immunogen: Homo sapiens (Human)
Post Translational Modifications Methylation of glutamine in the GGQ triplet by HEMK1.
Function Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. Involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.
Protein Name Large Ribosomal Subunit Protein Ml62
39s Ribosomal Protein L58 - Mitochondrial
Mrp-L58
Digestion Substraction 1
Ds-1
Immature Colon Carcinoma Transcript 1 Protein
Peptidyl-Trna Hydrolase Ict1 - Mitochondrial
Database Links Reactome: R-HSA-5368286
Reactome: R-HSA-5389840
Reactome: R-HSA-5419276
Cellular Localisation Mitochondrion
Alternative Protein Names Large Ribosomal Subunit Protein Ml62 protein
39s Ribosomal Protein L58 - Mitochondrial protein
Mrp-L58 protein
Digestion Substraction 1 protein
Ds-1 protein
Immature Colon Carcinoma Transcript 1 Protein protein
Peptidyl-Trna Hydrolase Ict1 - Mitochondrial protein
MRPL58 protein
DS1 protein
ICT1 protein

Information sourced from Uniprot.org

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