Function | Involved in glycerolipid synthesis and lipid metabolism. Catalyzes the formation of diacylglycerol, the precursor of triacylglycerol, by transferring the acyl chain of a fatty acyl-CoA to a monoacylglycerol, mainly at the sn-1 or sn-3 positions. It uses both sn-2-monoacylglycerol (2-acylglycerol) and sn-1-monoacylglycerol (1-acyl-sn-glycerol) equally well as substrates, and uses sn-3-monoacylglycerol (3-acyl-sn-glycerol) with lower efficiency. Probably not involved in absorption of dietary fat in the small intestine. |
Protein Name | 2-Acylglycerol O-Acyltransferase 1Acyl-Coa -Monoacylglycerol Acyltransferase 1Mgat1Diacylglycerol O-Acyltransferase Candidate 2Hdc2Diacylglycerol Acyltransferase 2-Like Protein 1Monoacylglycerol O-Acyltransferase 1 |
Database Links | Reactome: R-HSA-75109 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative Protein Names | 2-Acylglycerol O-Acyltransferase 1 proteinAcyl-Coa -Monoacylglycerol Acyltransferase 1 proteinMgat1 proteinDiacylglycerol O-Acyltransferase Candidate 2 proteinHdc2 proteinDiacylglycerol Acyltransferase 2-Like Protein 1 proteinMonoacylglycerol O-Acyltransferase 1 proteinMOGAT1 proteinDC2 proteinDGAT2L1 protein |
Information sourced from Uniprot.org