Post Translational Modifications | N- and O-glycosylated. Processed by matrix metalloproteinases (MMPs) including MMP9 and, to a lesser degree, by MMP2 upon angiogenic stimulation. |
Function | Extracellular matrix protein that plays significant roles in the vascular system and is required for the maintenance and stability of blood vessel. Affects several essential steps in angiogenesis including endothelial cell proliferation, migration, and tube formation. Positively regulates angiogenesis by acting as a ligand for CD93 receptor. |
Protein Name | Multimerin-2Emilin-3Elastin Microfibril Interface Located Protein 3Elastin Microfibril Interfacer 3Endoglyx-1 P125/P140 Subunit |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Protein Names | Multimerin-2 proteinEmilin-3 proteinElastin Microfibril Interface Located Protein 3 proteinElastin Microfibril Interfacer 3 proteinEndoglyx-1 P125/P140 Subunit proteinMMRN2 proteinEMILIN3 protein |
Information sourced from Uniprot.org