| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.2 Mu m filtered solution of 150 mM NaCl, 5 mM CaCl2, 50 mM Tris, pH 7.5. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.01 EU/Mu g of the protein by LAL method |
| Gene Symbol: | MMP10 |
| Gene ID: | 4319 |
| Uniprot ID: | MMP10_HUMAN |
| Immunogen Region: | Tyr18-Cys476 |
| Immunogen: | Recombinant Human MMP-10 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Tyr18-Cys476) of Human MMP-10 (Accession #NP_002416.1) fused with His at the C-terminus. |
| Immunogen Sequence: | YPLSGAAKEEDSNKDLAQQY LEKYYNLEKDVKQFRRKDSN LIVKKIQGMQKFLGLEVTGK LDTDTLEVMRKPRCGVPDVG HFSSFPGMPKWRKTHLTYRI VNYTPDLPRDAVDSAIEKAL KVWEEVTPLTFSRLYEGEAD IMISFAVKEHGDFYSFDGPG HSLAHAYPPGPGLYGDIHFD DDEKWTEDASGTNLFLVAAH ELGHSLGLFHSANTEALMYP LYNSFTELAQFRLSQDDVN |
| Function | Can degrade fibronectin, gelatins of type I, III, IV, and V.weakly collagens III, IV, and V. Activates procollagenase. |
| Protein Name | Stromelysin-2Sl-2Matrix Metalloproteinase-10Mmp-10Transin-2 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Stromelysin-2 proteinSl-2 proteinMatrix Metalloproteinase-10 proteinMmp-10 proteinTransin-2 proteinMMP10 proteinSTMY2 protein |
Information sourced from Uniprot.org
