| Short Description : | Recombinant-Human MLLT11-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Denatured |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.25 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MLLT11 |
| Gene ID: | 10962 |
| Uniprot ID: | AF1Q_HUMAN |
| Accession Number: | NP_006809 |
| Immunogen: | Human |
| Immunogen Region: | 1-90aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMRDPVSS QYSSFLFWRM PIPELDLSEL EGLGLSDTAT YKVKDSSVGK MIGQATAADQ EKNPEGDGLL EYSTFNFWRA PIASIHSFEL DLL |
| Tissue Specificity | Expressed in myoepithelial cells of normal breast tissue (at protein level). Highly expressed in thymus. Expressed in colon, small intestine, prostate and ovary. Not detected in peripheral blood lymphocytes and spleen. |
| Post Translational Modifications | Ubiquitinated, leading to degradation. |
| Function | Cofactor for the transcription factor TCF7. Involved in regulation of lymphoid development by driving multipotent hematopoietic progenitor cells towards a T cell fate. |
| Protein Name | Protein Af1q |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeContinuous Nuclear Export Is Followed By Degradation |
| Alternative Protein Names | Protein Af1q proteinMLLT11 proteinAF1Q protein |
Information sourced from Uniprot.org