| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.051ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This MGMT Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | MGMT |
| Gene ID: | 4255 |
| Uniprot ID: | MGMT_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. |
| Protein Name | Methylated-Dna--Protein-Cysteine Methyltransferase6-O-Methylguanine-Dna MethyltransferaseMgmtO-6-Methylguanine-Dna-Alkyltransferase |
| Database Links | Reactome: R-HSA-5657655 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Methylated-Dna--Protein-Cysteine Methyltransferase ELISA kit6-O-Methylguanine-Dna Methyltransferase ELISA kitMgmt ELISA kitO-6-Methylguanine-Dna-Alkyltransferase ELISA kitMGMT ELISA kit |
| output |
Information sourced from Uniprot.org