Human MGMT (O-6-Methylguanine DNA Methyltransferase) Sandwich ELISA Kit Kit (STJE0010574)

SKU:
STJE0010574
£465.50 - £636.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.051ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This MGMT Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: MGMT
Gene ID: 4255
Uniprot ID: MGMT_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Protein Name Methylated-Dna--Protein-Cysteine Methyltransferase
6-O-Methylguanine-Dna Methyltransferase
Mgmt
O-6-Methylguanine-Dna-Alkyltransferase
Database Links Reactome: R-HSA-5657655
Cellular Localisation Nucleus
Alternative ELISA Names Methylated-Dna--Protein-Cysteine Methyltransferase ELISA kit
6-O-Methylguanine-Dna Methyltransferase ELISA kit
Mgmt ELISA kit
O-6-Methylguanine-Dna-Alkyltransferase ELISA kit
MGMT ELISA kit
output

Information sourced from Uniprot.org