Tissue Specificity | |
Post Translational Modifications | |
Function | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. |
Protein Name | Methylated-Dna--Protein-Cysteine Methyltransferase6-O-Methylguanine-Dna MethyltransferaseMgmtO-6-Methylguanine-Dna-Alkyltransferase |
Database Links | Reactome: R-HSA-5657655 |
Cellular Localisation | Nucleus |
Alternative ELISA Names | Methylated-Dna--Protein-Cysteine Methyltransferase ELISA kit6-O-Methylguanine-Dna Methyltransferase ELISA kitMgmt ELISA kitO-6-Methylguanine-Dna-Alkyltransferase ELISA kitMGMT ELISA kit |
output | |
Information sourced from Uniprot.org