Human MFGE8 protein (Recombinant) (N-His) (STJP005231)

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STJP005231
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MFGE8-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MFGE8
Gene ID: 4240
Uniprot ID: MFGM_HUMAN
Immunogen Region: Met1-Cys335
Immunogen: Homo sapiens (Human)
Post Translational Modifications Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.
Function Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization. Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Medin: Main constituent of aortic medial amyloid.
Protein Name Lactadherin
Breast Epithelial Antigen Ba46
Hmfg
Mfgm
Milk Fat Globule-Egf Factor 8
Mfg-E8
Sed1 Cleaved Into - Lactadherin Short Form - Medin
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Reactome: R-HSA-977225
Cellular Localisation Membrane
Peripheral Membrane Protein
Secreted
Cytoplasmic Vesicle
Secretory Vesicle
Acrosome Membrane
Located In The Acrosomal Region Of Zona-Pellucida Bound Sperm
Alternative Protein Names Lactadherin protein
Breast Epithelial Antigen Ba46 protein
Hmfg protein
Mfgm protein
Milk Fat Globule-Egf Factor 8 protein
Mfg-E8 protein
Sed1 Cleaved Into - Lactadherin Short Form - Medin protein
MFGE8 protein

Information sourced from Uniprot.org