| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human METTL5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | METTL5 |
| Gene ID: | 29081 |
| Uniprot ID: | METL5_HUMAN |
| Immunogen Region: | Met1-Phe209 |
| Immunogen: | Homo sapiens (Human) |
| Function | Catalytic subunit of a heterodimer with TRMT112, which specifically methylates the 6th position of adenine in position 1832 of 18S rRNA. N6-methylation of adenine(1832) in 18S rRNA resides in the decoding center of 18S rRNA and is required for translation and embryonic stem cells (ESCs) pluripotency and differentiation. |
| Protein Name | Rrna N(6-Adenosine-Methyltransferase Mettl5Methyltransferase-Like Protein 5 |
| Cellular Localisation | NucleusPresynapsePostsynapse |
| Alternative Protein Names | Rrna N(6-Adenosine-Methyltransferase Mettl5 proteinMethyltransferase-Like Protein 5 proteinMETTL5 proteinDC3 proteinHSPC133 protein |
Information sourced from Uniprot.org
