Name: Human METAP2 protein (Recombinant) (N-His) (STJP013355)
SKU: STJP013355-100
Price: 694.83 USD
Availability: InStock

Human METAP2 protein (Recombinant) (N-His) (STJP013355)

SKU:

STJP013355-100

$694.83

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Short Description :	Recombinant-Human METAP2-N-His protein was developed from insect cells and has a target region of N-His. For use in research applications.
Applications:	ELISA/WB
Host:	Insect Cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation:	Unconjugated
Formulation:	Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 500mM NaCl, 10% Glycerol, pH 8.0.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:	< 1 EU/µg as determined by LAL test.

Function	Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.
Protein Name	Methionine Aminopeptidase 2 Map 2 Metap 2 Initiation Factor 2-Associated 67 Kda Glycoprotein P67 P67eif2 Peptidase M
Database Links	Reactome: R-HSA-2514859
Cellular Localisation	Cytoplasm About 30% Of Expressed Metap2 Associates With Polysomes
Alternative Protein Names	Methionine Aminopeptidase 2 protein Map 2 protein Metap 2 protein Initiation Factor 2-Associated 67 Kda Glycoprotein P67 protein P67eif2 protein Peptidase M protein METAP2 protein MNPEP protein P67EIF2 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP004853	Human METAP2 protein (Recombinant) (N-His) (STJP004853)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP012021	Human METAP2 protein (Recombinant-Active) (C-10*His) (STJP012021)	Insect Cells	ELISA/WB
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP003416	Human CCNB2 protein (Recombinant) (N-His) (STJP003416)	E.coli	ELISA/Immunogen/SDS-PAGE/WB

Human METAP2 protein (Recombinant) (N-His) (STJP013355)

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