Human MEPE (Matrix Extracellular Phosphoglycoprotein) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016945)

Human MEPE (Matrix Extracellular Phosphoglycoprotein) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016945)

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STJE0016945
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.29ng/mL
Detection Limit: 0.937-60ng/mL
Short Description : This MEPE Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: MEPE
Gene ID: 56955
Uniprot ID: MEPE_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity Detected in urine (at protein level). Expressed by osteoblasts. Expressed by stem cells in dental pulp. Expressed by mesenchymal cells in dental papilla and dental pulp. Expressed in teeth, specifically in decidious dentin. Expressed in ondotoblasts. Expressed in salivary glands. Secreted from oncogenic hypophosphatemic tumors.
Post Translational Modifications Phosphorylated on serine residues in the ASARM motif (in vitro) by FAM20C.the phosphorylation is important for the inhibition of bone mineralization. Cleaved by CTSB/cathepsin B.the cleavage is blocked by metalloprotease PHEX.
Function Promotes renal phosphate excretion and inhibits intestinal phosphate absorption. Promotes bone mineralization by osteoblasts and cartilage mineralization by chondrocytes. Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage. Promotes dental pulp stem cell proliferation and differentiation.
Protein Name Matrix Extracellular Phosphoglycoprotein
Osteoblast/Osteocyte Factor 45
Of45
Osteoregulin
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative ELISA Names Matrix Extracellular Phosphoglycoprotein ELISA kit
Osteoblast/Osteocyte Factor 45 ELISA kit
Of45 ELISA kit
Osteoregulin ELISA kit
MEPE ELISA kit
output

Information sourced from Uniprot.org

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