| Post Translational Modifications | Constitutively sumoylated. |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 7Hmed7Activator-Recruited Cofactor 34 Kda ComponentArc34Cofactor Required For Sp1 Transcriptional Activation Subunit 9Crsp Complex Subunit 9Mediator Complex Subunit 7Rna Polymerase Transcriptional Regulation Mediator Subunit 7 HomologTranscriptional Coactivator Crsp33 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110Reactome: R-HSA-9841922 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Mediator Of Rna Polymerase Ii Transcription Subunit 7 proteinHmed7 proteinActivator-Recruited Cofactor 34 Kda Component proteinArc34 proteinCofactor Required For Sp1 Transcriptional Activation Subunit 9 proteinCrsp Complex Subunit 9 proteinMediator Complex Subunit 7 proteinRna Polymerase Transcriptional Regulation Mediator Subunit 7 Homolog proteinTranscriptional Coactivator Crsp33 proteinMED7 proteinARC34 proteinCRSP9 protein |
Information sourced from Uniprot.org
