| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 27Cofactor Required For Sp1 Transcriptional Activation Subunit 8Crsp Complex Subunit 8Mediator Complex Subunit 27P37 Trap/Smcc/Pc2 SubunitTranscriptional Coactivator Crsp34 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110Reactome: R-HSA-9841922 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Mediator Of Rna Polymerase Ii Transcription Subunit 27 proteinCofactor Required For Sp1 Transcriptional Activation Subunit 8 proteinCrsp Complex Subunit 8 proteinMediator Complex Subunit 27 proteinP37 Trap/Smcc/Pc2 Subunit proteinTranscriptional Coactivator Crsp34 proteinMED27 proteinCRSP34 proteinCRSP8 protein |
Information sourced from Uniprot.org
